Deploying Palo Alto Prisma Access Zero Trust
When to Use
- When implementing enterprise-grade SASE with integrated ZTNA, SWG, CASB, and FWaaS
- When replacing both VPN and branch office firewalls with cloud-delivered security
- When needing advanced threat prevention (WildFire, DNS Security) for remote access traffic
- When deploying zero trust for both mobile users and remote network (branch) connections
- When integrating ZTNA with existing Palo Alto NGFW infrastructure via Strata Cloud Manager
Do not use for small organizations (< 200 users) where simpler ZTNA solutions suffice, for environments requiring only web application access without full network security, or when budget constraints preclude enterprise SASE licensing.
Prerequisites
- Prisma Access license (Business Premium or equivalent)
- Strata Cloud Manager (SCM) tenant configured
- GlobalProtect agent for endpoint deployment
- ZTNA Connector VM: 4 vCPU, 8GB RAM, 128GB disk (VMware, AWS, Azure, or GCP)
- Identity provider: Okta, Entra ID, Ping Identity (SAML 2.0)
- Palo Alto Cortex Data Lake for log storage
Workflow
Step 1: Configure Prisma Access Infrastructure in Strata Cloud Manager
Set up the cloud infrastructure for mobile user and remote network connections.
Strata Cloud Manager > Prisma Access > Infrastructure Settings:
Mobile Users Configuration:
- Service Connection: Auto-selected based on user location
- DNS Servers: 10.1.1.10, 10.1.1.11 (corporate DNS)
- IP Pool for Mobile Users: 10.100.0.0/16
- Authentication: SAML with Okta (Primary), Entra ID (Secondary)
- GlobalProtect Portal: portal.company.com
- GlobalProtect Gateway: Auto (nearest Prisma Access location)
Infrastructure Subnet:
- Range: 172.16.0.0/16
- Allocation: /24 per Prisma Access location
Step 2: Deploy ZTNA Connectors for Private Application Access
Install ZTNA Connectors to provide secure access to internal applications.
# Deploy ZTNA Connector on VMware (OVA)
# Download OVA from Strata Cloud Manager > Prisma Access > ZTNA Connectors
# AWS deployment via CloudFormation
aws cloudformation create-stack \
--stack-name prisma-ztna-connector \
--template-url https://prisma-access-connector-templates.s3.amazonaws.com/ztna-connector-aws.yaml \
--parameters \
ParameterKey=VpcId,ParameterValue=vpc-PROD \
ParameterKey=SubnetId,ParameterValue=subnet-PRIVATE \
ParameterKey=InstanceType,ParameterValue=m5.xlarge \
ParameterKey=TenantServiceGroup,ParameterValue=TSG_ID \
ParameterKey=ConnectorName,ParameterValue=dc-east-connector-01
# Verify connector registration
# Strata Cloud Manager > Prisma Access > ZTNA Connectors
# Status should show "Connected" with nearest Prisma Access location
# Deploy second connector for HA
# ZTNA Connector auto-discovers nearest Prisma Access location
# IPSec tunnel uses: ecp384/aes256/sha512 for IKE and ESP
# Bandwidth: up to 2 Gbps per connector
Step 3: Define Application Definitions and Access Policies
Create application definitions pointing to internal applications via ZTNA Connectors.
Strata Cloud Manager > Prisma Access > Applications:
Application 1: Internal Wiki
- FQDN: wiki.internal.corp
- Port: TCP 443
- ZTNA Connector: dc-east-connector-01
- Protocol: HTTPS
- Health Check: Enabled (HTTP GET /health)
Application 2: Source Code Repository
- FQDN: git.internal.corp
- Ports: TCP 22, 443
- ZTNA Connector: dc-east-connector-01, dc-east-connector-02
- Protocol: HTTPS, SSH
Application 3: Finance ERP
- FQDN: erp.internal.corp
- Port: TCP 443
- ZTNA Connector: dc-east-connector-01
- Protocol: HTTPS
- User Authentication: Required (re-auth every 2h)
Strata Cloud Manager > Policies > Security Policy:
Rule 1: Engineering Access to Dev Tools
Source: User Group "Engineering" (from Okta SAML)
Destination: Application "Source Code Repository", "Internal Wiki"
HIP Profile: "Managed Device with CrowdStrike"
Action: Allow
Logging: Enabled
Threat Prevention: Best Practice profile
Rule 2: Finance Access to ERP
Source: User Group "Finance"
Destination: Application "Finance ERP"
HIP Profile: "Compliant Device - High Security"
Action: Allow
SSL Decryption: Forward Proxy
DLP Profile: "Financial Data Protection"
Rule 3: Default Deny Private Apps
Source: Any
Destination: Any Private App
Action: Deny
Logging: Enabled
Step 4: Configure Host Information Profile (HIP) for Device Posture
Define device posture requirements using HIP checks.
Strata Cloud Manager > Objects > GlobalProtect > HIP Objects:
HIP Object: "CrowdStrike Running"
- Vendor: CrowdStrike
- Product: Falcon Sensor
- Is Running: Yes
- Minimum Version: 7.10
HIP Object: "Disk Encryption Enabled"
- Windows: BitLocker = Encrypted
- macOS: FileVault = Encrypted
HIP Object: "OS Patch Level"
- Windows: >= 10.0.22631
- macOS: >= 14.0
HIP Profile: "Managed Device with CrowdStrike"
- Match: "CrowdStrike Running" AND "Disk Encryption Enabled"
HIP Profile: "Compliant Device - High Security"
- Match: "CrowdStrike Running" AND "Disk Encryption Enabled" AND "OS Patch Level"
Step 5: Deploy GlobalProtect Agent to Endpoints
Roll out the GlobalProtect agent for secure connectivity.
# Deploy GlobalProtect via Intune (Windows)
# MSI download from Strata Cloud Manager > GlobalProtect > Agent Downloads
# GlobalProtect pre-deployment configuration
# pre-deploy.xml for automated portal connection:
cat > pre-deploy.xml << 'EOF'
<GlobalProtect>
<Settings>
<portal>portal.company.com</portal>
<connect-method>pre-logon</connect-method>
<authentication-override>
<generate-cookie>yes</generate-cookie>
<cookie-lifetime>24</cookie-lifetime>
</authentication-override>
</Settings>
</GlobalProtect>
EOF
# Verify GlobalProtect connection status
# GlobalProtect system tray > Settings > Connection Details
# Should show: Connected to nearest Prisma Access gateway
# IPSec tunnel established with full threat prevention
Step 6: Configure Logging and Monitoring
Set up Cortex Data Lake integration and monitoring dashboards.
Strata Cloud Manager > Prisma Access > Monitoring:
Log Forwarding:
- Cortex Data Lake: Enabled (all log types)
- SIEM Forwarding: Splunk HEC (https://splunk-hec.company.com:8088)
- Log Types: Traffic, Threat, URL, WildFire, GlobalProtect, HIP Match
Dashboard Monitoring:
- Mobile Users: Active connections, locations, bandwidth
- ZTNA Connectors: Health, latency, tunnel status
- Security Events: Threats blocked, DLP violations, HIP failures
- Application Usage: Top apps, top users, denied access attempts
Alerting:
- ZTNA Connector down: Email + PagerDuty
- HIP failure rate > 10%: Email to IT
- Threat detected on mobile user: SOC alert
Key Concepts
| Term | Definition |
|---|
| Prisma Access | Palo Alto's cloud-delivered SASE platform providing FWaaS, SWG, CASB, DLP, and ZTNA from a single architecture |
| ZTNA Connector | VM-based connector establishing IPSec tunnels from internal networks to Prisma Access for private application access |
| GlobalProtect | Endpoint agent providing secure connectivity to Prisma Access with HIP checks and always-on VPN |
| Host Information Profile (HIP) | Device posture checks evaluating endpoint security state (EDR, encryption, patches) before granting access |
| Strata Cloud Manager | Unified management console for Prisma Access, NGFW, and Prisma Cloud security policy |
| Cortex Data Lake | Cloud-based log storage and analytics platform for Palo Alto security telemetry |
Tools & Systems
- Prisma Access: Cloud-delivered SASE with integrated ZTNA, SWG, CASB, DLP, FWaaS
- Strata Cloud Manager (SCM): Unified policy management across Palo Alto security products
- GlobalProtect Agent: Endpoint connectivity agent with HIP data collection
- ZTNA Connector: Outbound-only tunnel connector for internal application access
- Cortex Data Lake: Centralized log storage with analytics and threat detection
- WildFire: Cloud-based malware analysis and prevention integrated with Prisma Access
Common Scenarios
Scenario: Enterprise SASE Migration for 5,000-User Organization
Context: A manufacturing company with 5,000 users across 15 offices is consolidating VPN, SWG, and branch firewalls into Prisma Access SASE. Users access 50+ internal applications and need consistent security regardless of location.
Approach:
- Deploy ZTNA Connectors at 3 data centers (2 per DC for HA) for internal application access
- Configure GlobalProtect with pre-logon connection for always-on security
- Define 50+ application definitions in SCM with FQDN and port mappings
- Create HIP profiles: Standard (encryption + AV), Enhanced (+ CrowdStrike + patches)
- Build security policies mapping user groups to applications with HIP requirements
- Enable threat prevention profiles (Anti-Spyware, Anti-Virus, WildFire, URL Filtering)
- Deploy GlobalProtect agent via SCCM to all 5,000 endpoints in phases
- Configure Cortex Data Lake forwarding to Splunk for SOC monitoring
- Decommission VPN concentrators and branch firewall appliances
Pitfalls: ZTNA Connector requires minimum 4 vCPU and 8GB RAM; under-provisioning causes latency. GlobalProtect pre-logon requires machine certificates for authentication before user login. HIP check intervals should be 60 seconds minimum to avoid performance impact. Plan for a 4-6 week pilot before full deployment.
Output Format
Prisma Access ZTNA Deployment Report
==================================================
Organization: ManufactureCorp
Deployment Date: 2026-02-23
INFRASTRUCTURE:
ZTNA Connectors: 6 (2x DC-East, 2x DC-West, 2x DC-EU)
Prisma Access Locations: 8 (auto-selected)
GlobalProtect Portal: portal.manufacturecorp.com
APPLICATION ACCESS:
Defined Applications: 52
Active ZTNA Connections: 3,247
Average Latency: 12ms
ENDPOINT DEPLOYMENT:
GlobalProtect Deployed: 4,812 / 5,000 (96.2%)
HIP Compliant: 4,567 / 4,812 (94.9%)
HIP Failures: 245 (top: missing patches 120, encryption 85)
SECURITY (last 30 days):
Threats Blocked: 1,234
DLP Violations: 89
URL Blocked: 45,678
WildFire Submissions: 2,345
