Matt Pocock-style docs-anchored grilling for a Research Operations plan — clinical study, R&D budget, market size, or product study. Walks the plan against the
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Apply Matt Pocock's grill-with-docs discipline to this plan / problem:
$ARGUMENTS
CLINICAL: "Is your primary endpoint a clinical outcome or a surrogate — and if surrogate, is it validated for this indication?" Recommended: clinical outcome unless the surrogate is on FDA's validated table. Canon: FDA Surrogate Endpoint Table; BEST glossary; ICH E9.
RD_FINANCE: "Is this spend in the research phase or the development phase, and can you evidence technical feasibility?" Recommended: research = expense; development = capitalize-candidate only with feasibility evidence, routed to a named finance owner. Canon: IAS 38; ASC 730.
MARKET: "Is your TAM top-down or bottoms-up — and have you computed it both ways to triangulate?" Recommended: both; reconcile the delta before quoting a number. Canon: Bessemer / a16z market-sizing; Fermi estimation.
PRODUCT: "Is this study generative (discover problems) or evaluative (test a solution)?" Recommended: name it first; the method follows. Canon: Rohrer's UX-research methods landscape (NN/g).
"What's your confidence level, and what are the three assumptions the answer rests on?" Recommended: state confidence (high/moderate/low) and surface the assumptions before any number.
"Who is the human owner who signs this output?" Recommended: a named clinician/biostatistician (clinical), a named finance controller (finance), a named decision-maker (market/product) — not "the team".
Only after branches 1-4 are locked, invoke /cs:research-ops with the synthesized inquiry.
Q[i]/[total]: [precise question]
Recommended: [answer + canon-cited rationale]
(Confirm, or override?)
/cs:research-ops <synthesized>research-ops-grill-{timestamp}.mdengineering/grill-me (Matt Pocock) — generic.engineering/grill-with-docs (Matt Pocock) — codebase + ADR-anchored for engineering. This is Research-Ops-domain grilling against the research canon./cs:research-ops — executes routing. This interrogates first.